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We all know skin changes with age — it gets thinner, drier, and loses that youthful bounce. One of the lesser-known drivers behind this transformation? A molecule called NAD⁺ (nicotinamide adenine dinucleotide). Think of NAD⁺ as the fuel that powers your skin cells’ little engines (mitochondria). It helps convert nutrients into energy, repairs DNA, and supports protective enzymes that keep skin resilient. The catch: as we age, our NAD⁺ levels decline, which means our skin cells can’t work as efficiently as they once did. The result? Slower repair, less collagen, more visible fine lines, and thinner, more fragile skin.
Researchers have been investigating whether NAD⁺ precursors — compounds that the body can turn into NAD⁺ — could help restore this lost vitality. Two of the most promising are nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), both forms of vitamin B3. When tested in human skin cells, these compounds were able to increase NAD⁺/NADH levels and stimulate procollagen-1 production, which is critical for maintaining firm, smooth skin. Even more exciting, research suggests that combining niacinamide with certain peptides and plant extracts may support the appearance of firmer, smoother, more youthful-looking skin.
What does this mean for you? While more research is needed, especially in large, long-term human studies, the science suggests that boosting NAD⁺ may be a smart way to help skin appear more energized, resilient, and youthfully radiant over time. Instead of only focusing on surface fixes, future skincare might tap into cellular bioenergetics — essentially giving your skin the fuel it needs to look its most vibrant.
Here is the study: https://academic.oup.com/bjd/article-abstract/169/...
Osborne, R., Carver, R. S., Mullins, L. A., & Finlay, D. R. (2013). Practical application of cellular bioenergetics to the care of aged skin. British Journal of Dermatology, 169(s2), 32–38.
Parlor Games products are not intended to treat, cure, prevent, or mitigate disease or other medical conditions. Our products are not the subject of the studies discussed herein, and we do not claim that our products will have the same effects as those discussed in these articles. This information is being provided for educational purposes only, and is not intended to replace the advice of a medical professional.
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Disclaimer: The information provided above is intended for educational and informational purposes only. Statements made have not been evaluated by the FDA nor are they intended to treat or diagnose. Any health concerns should be discussed and evaluated by your primary health care provider.
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Disclaimer: The information provided above is intended for educational and informational purposes only. Statements made have not been evaluated by the FDA nor are they intended to treat or diagnose. Any health concerns should be discussed and evaluated by your primary health care provider.
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