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Mood Swings & Your Hormones
07/16/2025

Feeling like you’re on a hormonal rollercoaster? Turns out, wild mood swings aren’t just in your head—they’re in your hormones.

What the research investigated: The link between fluctuations in estrogen and progesterone levels and mood instability in women during the perimenopausal transition.

Study design: A cohort study tracking hormone levels and mood symptoms over time in perimenopausal women showing depressive symptoms. Researchers monitored cyclical estrogen and progesterone changes and correlated them with mood assessments.

Key findings:

  • Greater hormone level variability was strongly associated with increased mood instability and depressive symptoms.
  • Both lower progesterone and erratic estrogen correlated with worsened emotional regulation.
  • The study underscored the importance of hormonal stability for mood health during perimenopause.

🔗 View the full study here.