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Menopause and Urogynecologic Health

This article looked at the link between estrogen receptors, estrogen levels, and the increase in Pelvic Floor Dysfunction (PFD) and UTI's in menopause.

Researchers theorized that, as we age and our estrogen levels decline, there would be an increase in these two outcomes. Gathering the data to do a literature review and summary confirmed this, however, the authors note that age must also be considered and that it cannot be solely attributed to the menopause transition.

Per the study, "The abundance of estrogen receptors in the urogenital tract explains why the natural reduction of endogenous estrogen, the hallmark of menopause, can cause or potentiate PFDs and rUTIs. A substantial body of epidemiological literature suggests an association between menopause, and PFDs and rUTIs; however, the ability to separate this association from age and other comorbid conditions makes it difficult to draw definitive conclusions on the role of menopause alone in the development and/or progression of PFDs."

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376984/