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How Safe & Effective is Estriol for Vaginal Atrophy?

Research on Safety and Efficacy of Topical Estrogens on vulvovaginal atropy


Whilst different creams have to be considered for safety, (i.e., estradiol creams are stronger and pose more of a risk), overall, for women suffering with multiple symptoms of vaginal atrophy due to menopause, topical estriol creams are a great option! This is key because typically, when women have one symptom, such as vaginal atrophy, they often have others, such as increased UTI or incontinence. The use of topical estriol to treat one symptom has a domino effect and will help improve the overall tone and structure of the vaginal tissue, and help treat other problems. "Compared with placebo, vaginal estrogens improved dryness, dyspareunia, urinary urgency, frequency, and stress urinary incontinence (SUI) and urgency urinary incontinence (UUI). Urinary tract infection rates decreased."

You can view the whole study here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855283/