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How Cortisol Affects the Gut
02/11/2025

Research has explored how constipation and diarrhea during the menopause transition relate to age, hormonal shifts, and stress-related factors — including cortisol levels and perceived tension.

Methods: Women aged 35–55 were followed from 1990 to 2013, with data collected annually through health diaries, questionnaires, and urine samples. These samples were tested for hormones like E1G, FSH, testosterone, cortisol, and others. Researchers used statistical modeling to see how changes in constipation and diarrhea were related to these factors.

Results:

  • Constipation: Age, being in the late reproductive stage, and stress (tension and anxiety) were linked to increased severity of constipation. However, cortisol (a stress hormone) was negatively associated with constipation. After adjusting for other factors, only tension and cortisol remained significant predictors of constipation severity.
  • Diarrhea: Age and certain hormones were linked to reduced diarrhea severity, while stress and anxiety were associated with more noticeable changes. In the final model, tension and age were the main predictors of diarrhea severity.

Conclusions: Reproductive hormones had little impact on constipation or diarrhea during menopause, but stress — including tension, anxiety, and cortisol levels — played a significant role. The study suggests these stress factors warrant further exploration in relation to digestive changes during menopause.

Link: https://journals.lww.com/menopausejournal/abstract/2018/06000/constipation_and_diarrhea_during_the_menopause.9.aspx

This article is for educational and general wellness purposes only. It is not medical advice and is not intended to diagnose, treat, cure, or prevent any disease. If you are noticing changes in your body or have questions about your health, please consult a knowledgeable healthcare provider.

Parlor Games products are not intended to treat, cure, prevent, or mitigate disease or other medical conditions. Our products are not the subject of the studies discussed herein, and we do not claim that our products will have the same effects as those discussed in these articles. This information is being provided for educational purposes only, and is not intended to replace the advice of a medical professional.